Methods for preparing capecitabine and beta-anomer-rich...

Details Methods for preparing capecitabine and beta-anomer-rich... Methods for preparing capecitabine and beta-anomer-rich...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01)

Patent

CA 2704815

The present invention relates to a method for preparing capecitabine and a method for preparing a .beta.-anomer-rich trialkyl carbonate compound used therein, and a highly pure capecitabine can be efficiently prepared with a high yield by the method of the present invention using the .beta.-anomer-rich trialkyl carbonate compound as an intermediate.

La présente invention porte sur un procédé de préparation de la capécitabine et sur un procédé de préparation d'un composé trialkyl carbonate riche en ß-anomère utilisé dans celui-ci, et une capécitabine hautement pure peut être efficacement préparée avec un haut rendement par le procédé de la présente invention à l'aide du composé trialkyl carbonate riche en ß-anomère comme intermédiaire.

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