C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/06 (2006.01)
Patent
CA 2586176
The invention relates to methods for preparing indalzole compounds having formula (I) or pharmaceutically acceptable salts or solvates thereof. Compounds of the formula (I) are useful as anti-angiogenesis agents and as agents for modulating and/or inhibiting the activity of protein kinases, thus providing treatments for cancer or other diseases associated with cellular proliferation mediated by protein kinases.
L'invention concerne des méthodes de préparation de composés d'indazole de formule (I) ou des sels ou des solvates correspondants acceptables pharmaceutiquement. Des composés de formule (I) sont utilisés en tant qu'agents antiangiogéniques et agents de modulation et/ou d'inhibition de l'activité de protéines kinases, ce qui permet donc fournir des traitements contre le cancer ou d'autres maladies associées à la prolifération cellulaire médiée par protéines kinases.
Babu Srinivasan
Dagnino Raymond Jr.
Ouellette Michael Allen
Shi Bing
Tian Qingping
Pfizer Inc.
Smart & Biggar
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