Methods for preparing metal-carborane complexes for...

Details Methods for preparing metal-carborane complexes for... Methods for preparing metal-carborane complexes for...

C - Chemistry, Metallurgy

07

F

C07F 15/00 (2006.01) A61K 51/00 (2006.01) C07F 13/00 (2006.01)

Patent

CA 2477020

The present invention relates to a method of preparing metal-carborane complexes comprising reacting a salt of the formula: [M(CO)3(X m)3](1 + 3m), wherein M is selected from a radioisotope of rhenium (Re), technetium (Tc) and any other radioisotope binding in the same fashion, X is the same of different and is, independently, any suitable ligand and m is the formal charge for ligand X, with a nido-dicarbollide dianion in the presence of a hard base. In an embodiment of the invention, the hard base is a source of fluoride.

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