Methods for preparing new taxoids and pharmaceutical...

Details Methods for preparing new taxoids and pharmaceutical... Methods for preparing new taxoids and pharmaceutical...

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01) A61K 31/335 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2438829

Methods of preparing methylthionethyloxy taxoids of formula (XXXIV) from baccatin and .beta.-lactam are presented. These new taxoids display noteworthy anti-tumor and anti-leukemic properties.

Procédés de préparation de méthylthiométhyloxy taxoïdes représentés par la formule (XXXIV), à partir de baccatine et de .beta.-lactame. Ces nouveaux taxoïdes possèdent des propriétés antitumorales et antileucémiques remarquables.

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