Methods for preventing and treating cancer metastasis and...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/24 (2006.01) A61K 6/00 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) A61P 35/04 (2006.01) C12Q 1/04 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2505994

M-CSF antagonists are provided, along with pharmaceutical compositions containing a M-CSF antagonist, kits containing a pharmaceutical composition, methods of preventing and treating bone metastases in a subject afflicted with metastatic cancer, methods of screening for M-CSF antagonists, and uses of M- CSF in medicine and preparing medicaments for preventing and treating bone metastases and tumor growth.

La présente invention a trait à des antagonistes du facteur stimulant de la prolifération de macrophages (M-CSF), ainsi que des compositions pharmaceutiques contenant un antagoniste de M-CSF, des trousses contenant une composition pharmaceutique, des procédés de prévention et de traitement de métastases osseuses chez un sujet atteint de métastase cancéreuse, des procédés de criblage pour des antagonistes de M-CSF, et des utilisations de M-CSF dans le domaine médical et la préparation de médicaments pour la prévention et le traitement de métastase osseuses et de croissance tumorale.

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