C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/02 (2006.01) A61K 31/7056 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2616702
The invention relates to methods for preventing or treating metabolic disorders, for improving glycemic control, for preventing progression from impaired glucose tolerance, insulin resistance and/or from metabolic syndrome to type 2 diabetes mellitus, for preventing or treating of complications of diabetes mellitus, for reducing the weight, for preventing or treating the degeneration of pancreatic beta cells, for treating hyperinsulinemia and insulin resistance and diabetes type 1, in patients in need thereof by administering a pharmaceutical composition comprising a pyrazole-O-glycoside as defined in claim 1 , or a prodrug thereof, or a pharmaceutically acceptable salt thereof.
La présente invention concerne des méthodes permettant de prévenir ou de traiter des troubles métaboliques, d'améliorer le contrôle de la glycémie, d'empêcher la progression d'une diminution de la tolérance au glucose, d'une résistance à l'insuline et/ou d'un syndrome métabolique en diabète sucré de type 2, de prévenir ou de traiter les complications du diabète, de réduire le poids, de prévenir ou de traiter la dégénérescence des cellules bêta du pancréas, de traiter l'hyperinsulinémie, la résistance à l'insuline et le diabète de type 1 chez des patients nécessitant un tel traitement, lesquelles méthodes consistent à administrer au patient une composition pharmaceutique comprenant un pyrazole-O-glycoside tel que défini dans la revendication 1, ou un promédicament de celui-ci ou un sel pharmaceutiquement acceptable de celui-ci.
Barsoumian Edward Leon
Dugi Klaus
Eickelmann Peter
Fujita Koichi
Hatanaka Toshihiro
Ajinomoto Co. Inc.
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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