A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/135 (2006.01)
Patent
CA 2478026
The present disclosure is directed to methods for alleviating the symptoms associated with peripheral neuropathy by administering R(-)- desmethylselegiline, S(+) desmethylselegiline, or a combination of the two. The neuropathy may be the result of a genetically inherited condition, a systemic disease, or exposure to a toxic agent. The disclosure is also directed to a method for treating patients with cancer by administering a chemotherapeutic agent known to have a toxic affect on peripheral nerves together with R(-)-desmethylselegiline, S(+) desmethylselegiline, or a mixture of the two.
L'invention concerne des procédés permettant de soulager les symptômes associés à la neuropathie périphérique par administration de R(-)-desmethylselegiline, S(+) desmethylselegiline, ou une combinaison des deux. Cette neuropathie peut résulter d'une condition génétique, d'une maladie systémique, ou d'une exposition à un agent toxique. L'invention porte aussi sur un procédé de traitement de patients atteints d'un cancer par administration d'un agent chimiothérapeutique connu pour présenter un effet toxique sur les nerfs périphériques ainsi que de R(-)-desmethylselegiline, S(+) desmethylselegiline, ou un mélange des deux.
Blume Cheryl D.
Disanto Anthony R.
Ridout & Maybee Llp
Somerset Pharmaceuticals Inc.
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