Methods for preventing headaches

Details Methods for preventing headaches Methods for preventing headaches

A - Human Necessities

01

N

A01N 43/12 (2006.01) A61K 31/4535 (2006.01)

Patent

CA 2300821

A method of preventig headhache in a human which comprises the administration to a human in need thereof of an effective amount of a compound of formula (I) wherein R1 and R3 are, independently, -H, -CH3, -CO(C1-C6 alkyl), or -COAr, where Ar is optionally substituted phenyl; R3 is selected from the group consisting of pyrrolidine, piperidine, and hexamethyleneimino; or a pharmaceutically acceptable salt or solvate thereof.

L'invention concerne un procédé permettant de prévenir les maux de tête chez un sujet humain. Ce procédé consiste à administrer au sujet une quantité efficace d'un composé présentant la formule (I). Dans cette dernière, R?1¿ et R?3¿ sont, indépendamment, -H, -CH¿3?, -CO(alkyle C¿1?-C¿6?), ou -COAr, où Ar est éventuellement du phényle substitué; R?3¿ est sélectionné dans le groupe se composant de pyrrolidine, pipéridine, et héxaméthylèneimino; ou un sel pharmaceutiquement acceptable ou un solvate de ce dernier.

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