A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/55 (2006.01) A61K 31/726 (2006.01) A61K 31/727 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2535446
The present invention relates to therapeutic methods for preventing or reducing neurological events utilizing a glycosaminoglycan and a serpin, including complexes and conjugates thereof. Methods of the present invention may be advantageous for preventing or reducing neurological events prior to, or during medical or surgical procedures, and after a neurological event. In particular, the present invention deals with neurological events associated with the generation of emboli that can lodge in the brain and/or cerebral circulation during cardiac surgery.
L'invention porte sur des méthodes thérapeutiques de prévention ou réduction des accidents neurologiques utilisant un glycosaminoglycan et une serpine et leurs complexes ou conjugués. Lesdites méthodes peuvent prévenir ou réduire les accidents neurologiques avant ou pendant des actes chirurgicaux ou après leur survenance, et en particulier les accidents neurologiques associés à la formation emboles pouvant se loger dans le cerveau et/ou la circulation cérébrale suite à une intervention cardiaque.
Berry Leslie Roy
Chan Anthony Kam Chuen
Hirsh Jack
Klement Petr
Tressel Paul
Hamilton Civic Hospitals Research Development Inc.
Mccarthy Tetrault Llp
Mcmaster University
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