Methods for producing acyloxyacyl hydrolase

C - Chemistry – Metallurgy – 12 – N

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C12N 15/55 (2006.01) A61K 38/46 (2006.01) C12N 1/19 (2006.01) C12N 5/10 (2006.01) C12N 9/14 (2006.01) C12N 15/62 (2006.01) C12N 15/79 (2006.01)

Patent

CA 2091242

2091242 9204444 PCTABS00011 Methods are disclosed for producing acyloxyacyl hydrolase. The protein is produced from eukaryotic host cells transformed or transfected with DNA construct(s) containing information necessary to direct the expression of acyloxyacyl hydrolase. The DNA constructs generally include the following operably linked elements: a transcriptional promoter; DNA sequence encoding acyloxyacyl hydrolase, the small subunit of acyloxyacyl hydrolase or the large subunit of acyloxyacyl hydrolase; and a transcriptional terminator. In addition, isolated DNA sequences encoding acyloxyacyl hydrolase and isolated DNA sequences encoding the small or large subunit of acyloxyacyl hydrolase are disclosed.

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