G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01) C07H 21/00 (2006.01) C07K 1/12 (2006.01) C12P 21/06 (2006.01) C12Q 1/34 (2006.01) C12Q 1/37 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2221727
Methods of producing biopolymer ladders and their use to obtain structural information about the biopolymer. The ladders are produced by settling up catalytic cleavage and terminating reactions at the end of biopolymer molecules. The terminating reactions terminate cleavage of a percentage of the biopolymer molecules at each round of cleavage.
L'invention se rapporte à des procédés de production d'échelles de biopolymères et à leur utilisation permettant d'obtenir des informations structurelles sur le biopolymère. On produit ces échelles en établissant un clivage catalytique et des réactions terminales à l'extrémité des molécules des biopolymères. Les réactions terminales terminent le clivage d'un pourcentage de molécules de biopolymères à chaque série de clivage.
Chait Brian T.
Clark Steven M.
Kent Stephen B.
Wang Rong
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Ciphergen Biosystems Inc
The Rockefeller University
The Scripps Research Institute
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