Methods for producing enucleated erythroid cells derived...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/073 (2010.01) C12N 5/078 (2010.01)

Patent

CA 2722766

Methods for generating enucleated erythroid cells using pluripotent stem cells are provided. The methods permit the production of large numbers of cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications. Methods for generating megakaryocyte and platelets are also provided.

La présente invention a trait à des procédés de production de cellules érythrocytaires énuclées à partir de cellules souches pluripotentes. Ces procédés permettent la production d'un grand nombre de cellules. Les cellules obtenues par les procédés de l'invention peuvent être utilisées pour diverses applications cliniques, thérapeutiques et de recherche. L'invention concerne également des procédés de production de mégacaryocytes et de plaquettes.

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