Methods for producing hair microfollicles and de novo...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/071 (2010.01) A61K 35/36 (2006.01) A61L 27/60 (2006.01) A61P 17/14 (2006.01) C12M 1/02 (2006.01)

Patent

CA 2719769

The present invention relates to a method for producing hair microfollicles comprising the steps of: a) providing de novopapillae, b) providing other cell populations selected from the group of fibroblasts, keratinocytes and melanocytes, and co--culturing the de novopapillae with at least one other cell population in non-adherent culture vessels.The present invention relates also to methods of producing de novo papillae usable in said method for producing hair microfollicles.

La présente invention concerne un procédé pour produire des microfollicules capillaires, comprenant les étapes consistant (a) à produire des papilles de novo, (b) à produire d'autres populations de cellules choisies dans le groupe constitué de fibroblastes, de kératinocytes et de mélanocytes, et à co-cultiver les papilles de novo avec au moins une autre population de cellules dans des récipients de culture à non-adhérence. La présente invention concerne en outre des procédés de production de papilles de novo utilisables dans ledit procédé pour produire des microfollicules capillaires.

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