Methods for pulmonary delivery of interleukin-2

Details Methods for pulmonary delivery of interleukin-2 Methods for pulmonary delivery of interleukin-2

A - Human Necessities

61

K

A61K 9/72 (2006.01) A61K 9/14 (2006.01) A61K 9/19 (2006.01) A61K 38/20 (2006.01) A61K 47/26 (2006.01) A61K 9/16 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2395887

Methods for administering interleukin-2 (IL-2) or variants thereof via pulmonary inhalation are provided. The methods comprise preparing a pharmaceutical composition comprising IL-2 or variants thereof for subsequent delivery as an aqueous or nonaqueous solution or suspension or a dry powder form. These compositions may further comprise a surfactant in an amount sufficient to enhance absorption of the composition following pulmonary inhalation of the composition. When used in the delivery methods of the invention, these highly absorbable compositions result in enhanced bioavailability of IL-2.

L'invention concerne des procédés d'administration d'interleukine-2 (IL 2) ou de variantes de celle-ci par inhalation pulmonaire. Ces procédés comprennent la préparation d'une composition pharmaceutique comprenant IL-2 ou des variantes de celle-ci, afin de les administrer comme une solution ou une suspension aqueuse ou non aqueuse ou sous forme de poudre sèche. Ces compositions peuvent, en outre, comprendre un surfactant en quantité suffisante, afin d'améliorer l'absorption de la composition par inhalation pulmonaire. Lorsqu'elles sont utilisées dans les procédés d'administration de la présente invention, ces compositions à absorption élevée présentent une biodisponibilité améliorée de IL-2.

Affiliated with

Also associated with

Rating

Methods for pulmonary delivery of interleukin-2 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for pulmonary delivery of interleukin-2, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for pulmonary delivery of interleukin-2 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1510139