Methods for radiolabelling synthetic polymers

A - Human Necessities – 61 – K

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A61K 51/02 (2006.01) A61K 49/08 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2721835

The present invention relates to a method for preparing a radiolabeled synthetic polymer, the method comprising contacting a synthetic polymer with a carbon encapsulated nanoparticle composite having a radioactive particulate core in an aqueous medium comprising an electrolyte concentration or pH selected to promote short-range attractive forces between the nanoparticles and the synthetic polymer by attenuating long- range electrostatic repulsive forces.

Linvention concerne un procédé de préparation dun polymère synthétique radiomarqué. Ce procédé consiste à mettre en contact un polymère synthétique avec un composite de nanoparticules encapsulées dans du carbone, contenant un noyau particulaire radioactif, dans un milieu aqueux présentant une concentration délectrolyte ou un pH sélectionné(e) pour favoriser des forces dattraction courte portée entre les nanoparticules et le polymère synthétique, par atténuation des forces de répulsion électrostatiques longue portée.

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