Methods for reducing biofilm formation in infectious bacteria

Details Methods for reducing biofilm formation in infectious bacteria Methods for reducing biofilm formation in infectious bacteria

A - Human Necessities

61

K

A61K 39/40 (2006.01) A61K 39/395 (2006.01) C07K 16/12 (2006.01) C07K 16/44 (2006.01)

Patent

CA 2566588

The present invention provides methods of preventing or inhibiting biofilm formation by a population of bacteria, said method comprising the administration to the population of an antibody to a lactone or lactone- derived signal molecule secreted by bacteria. The invention therefore also provides methods for the treatment of bacterial infection in biofilm formation is prevented or inhibited.

Cette invention concerne des procédés pour prévenir ou inhiber la formation de biofilm par une population de bactéries, ce procédé consistant à administrer à cette population un anticorps contre une lactone ou contre une molécule signal dérivée de lactone sécrétée par ces bactéries. Cette invention concerne également des procédés pour traiter une infection bactérienne dans laquelle la formation de biofilm est empêchée ou inhibée.

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