Methods for reducing protein aggregation

Details Methods for reducing protein aggregation Methods for reducing protein aggregation

A - Human Necessities

61

K

A61K 47/18 (2006.01) C07K 1/00 (2006.01) C07K 14/755 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2646934

Methods of reducing aggregation of a protein or proteins in a formulation, and protein formulations having reduced aggregation properties are provided. The methods and formulations described herein maintain the biological activity of a protein and increase the shelf life of protein formulations.

L'invention concerne des méthodes permettant de réduire l'agrégation d'une ou de plusieurs protéines dans une préparation, ainsi que des préparations à base de protéines présentant des propriétés d'agrégation réduite. Les méthodes et préparations selon l'invention permettent de maintenir l'activité biologique d'une protéine et d'augmenter la durée de conservation de préparations à base de protéines.

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