A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 39/395 (2006.01)
Patent
CA 2597059
The present invention relates to a method for inhibiting a disease response in a subject comprising contacting dead or dying cells exposing an antigen selected from the group consisting of a phosphorylcholine (PC) determinant, a phosphatidyl serine (PS) determinant, a MDA determinant, and cardiolipin in the subject, with an antibody or recombinant protein that recognizes and binds the antigen that is exposed on the dead or dying cells, thereby inhibiting the pathologic response in the subject.
L'invention concerne une méthode pour inhiber une réponse pathologique chez un sujet. Cette méthode consiste à mettre en contact des cellules mortes ou mourantes exposant un antigène sélectionné dans le groupe comprenant un déterminant de phosphorylcholine (PC), un déterminant de phosphatidyl sérine (PS), un déterminant de MDA, une cardiolipine, chez le patient, avec un anticorps ou une protéine recombinante reconnaissant et se liant à l'antigène qui est exposé sur les cellules mortes ou mourantes, ce qui permet d'inhiber la réponse pathologique chez ce patient.
Cassan Maclean
The Regents Of The University Of California
LandOfFree
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