C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/30 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2499130
The present invention provides methods for inhibiting cancerous growth of a cell using an antibody or an antigen-binding portion thereof which binds to an epitope of EphB4 polypeptide. Purified antibodies of EphB4 are also provided. The invention also provides methods for preventing or treating cancer. The invention also relates to methods of identifying agents that can inhibit cancerous growth of a cell.
L'invention concerne des procédés destinés à inhiber la croissance cancéreuse d'une cellule au moyen d'un anticorps ou d'une partie de liaison à l'antigène de celui-ci qui se lie à un épitope du polypeptide EphB4. L'invention concerne également des anticorps purifiés de EphB4. Cette invention concerne enfin des procédés destinés à prévenir ou à traiter le cancer, ainsi que des procédés destinés à identifier des agents pouvant inhiber la croissance cancéreuse d'une cellule.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Queen Elizabeth Hospital Research Foundation Inc.
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