Methods for regulating gastrointestinal motility

Details Methods for regulating gastrointestinal motility Methods for regulating gastrointestinal motility

A - Human Necessities

61

K

A61K 38/26 (2006.01) A61P 1/00 (2006.01) C07K 14/605 (2006.01)

Patent

CA 2262647

Methods for reducing gastric motility and delaying gastric emptying for therapeutic and diagnostic purposes are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist. Methods for treating conditions associated with elevated, inapropriate, or undesired post-prandial blood glucose levels are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist alone or in conjunction with other anti- gastric emptying agents.

L'invention concerne des méthodes qui permettent de réduire la motilité gastrique et de retarder la vidange gastrique à des fins thérapeutiques ou diagnostiques. Les méthodes comprennent l'administration d'une dose efficace d'une exendine ou d'un agoniste de l'exendine. On décrit des méthodes de traitement d'états associées à des nivaux de glucose sanguin élevés, inappropriés ou indésirés, après manger, lesdites méthodes comprenant l'administration d'une dose efficace d'une exendine ou d'un agoniste de l'exendine seule ou en même temps que des agents de vidange anti-gastriques.

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