Methods for regulating levels of zinc, cadmium and calcium...

A - Human Necessities – 61 – K

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A61K 33/24 (2006.01) A61P 7/12 (2006.01) A61P 9/12 (2006.01) A61P 19/10 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2468154

Methods and compositions are provided for decreasing PGE2:PGF2.alpha., regulating ratios of zinc:cadmium and regulating the concentration of zinc, calcium and zinc-containing and PGE2-dependent matrix metalloproteinases in body fluids and tissues of a human. Elevated or otherwise unregulated levels of PGE2, zinc and calcium and elevated concentrations of zinc-containing and PGE2-dependent matrix metalloproteinases have been found to be associated with the development of certain diseases.

L'invention concerne des procédés et des compositions destinés à réduire, chez l'homme, le rapport PGE2:PGF2.alpha., à réguler les rapports zinc:cadmium et à réguler les concentrations de zinc, de calcium et de métalloprotéinase à zinc et de matrice à dépendance PGE2 dans des tissus et des fluides corporels. Il a été trouvé que des taux élevés ou non régulés de PGE2, de zinc et de calcium et des concentrations élevées de métalloprotéinases à zinc et de matrice à dépendance PGE2 sont associés au développement de certaines maladies.

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