Methods for regulating neurotransmitter systems by inducing...

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01) A61K 49/00 (2006.01)

Patent

CA 2643802

The present invention relates to methods for regulating neurotransmitter systems by inducing a counteradaptation response. According to one embodiment of the invention, a method for regulating a neurotransmitter includes the step of repeatedly administering a ligand for a receptor in the neurotransmitter system, with a ratio of administration half-life to period between administrations of no greater than 1/2. The methods of the present invention may be used to address a whole host of undesirable mental, neurological and physiological conditions.

La présente invention concerne des méthodes de régulation des systèmes neurotransmetteurs par induction d'une réponse de contre-adaptation. Selon l'un des modes de réalisation de l'invention, une méthode de régulation d'un neurotransmetteur comprend l'étape d'administration renouvelée d'un ligand pour un récepteur dans le système neurotransmetteur, le rapport de la demi-vie d'administration sur l'intervalle entre les administrations ne dépassant pas ½. Les méthodes de la présente invention peuvent être utilisées dans le cadre de nombreuses affections mentales, neurologiques et physiologiques indésirables.

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