A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 8/63 (2006.01) A61Q 19/00 (2006.01) A61Q 19/06 (2006.01)
Patent
CA 2373158
The present invention relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of a composition comprising: a) a safe and effective amount of one or more phytosterols selected from the group consisting of .beta.-sitosterol, campesterol, brassicasterol, .DELTA.5-avennasterol, lupenol, .alpha.-spinasterol, stigmasterol, their derivatives, and combinations thereof; and b) a dermatologically acceptable carrier for the phytosterol. In additional embodiments, the above composition is suitable for thickening skin and preventing, retarding, and/or treating atrophy of mammalian skin, preventing, retarding, and/or treating the appearance of dark, under-eye circles and/or puffy eyes, preventing, retarding, and/or treating sallowness of mammalian skin, preventing and/or retarding tanning of mammalian skin, regulating and/or reducing the size of pores in mammalian skin, desquamating, exfoliating, and/or increasing turnover of mammalian skin, regulating oily/shiny appearance, preventing/retarding post-inflammatory hyperpigmentation in mammalian skin, and preventing and/or treating the appearance of cellulite in mammalian skin.
Cette invention concerne des méthodes de régulation de l'état de tissus kératiniques chez des mammifères. Cette méthode consiste en l'application topique, chez un mammifère qui a besoin d'un tel traitement, d'une dose efficace d'une composition comprenant : a) une dose sans danger et efficace d'un ou plusieurs phytostérols pris dans le groupe composé de .beta.-sitosterol, campesterol, brassicasterol, .DELTA.5-avennasterol, lupenol, .alpha.-spinasterol, stigmasterol, de leurs dérivés et de combinaisons des composés précités ; et b) un vecteur acceptable pour le phytostérol. Selon d'autres modes de réalisation, la composition susmentionnée permet, chez un mammifère, d'augmenter l'épaisseur de la peau et d'en prévenir, ralentir et/ou traiter l'atrophie ; de prévenir, de ralentir et/ou de traiter les cercles sombres sous les yeux et les yeux gonflés, de prévenir, de ralentir et/ou de traiter le teint jaunâtre, de prévenir et/ou de ralentir le bronzage, de réguler et/ou de réduire la taille des pores, de desquamer, exfolier la peau et d'en accélérer le renouvellement, d'atténuer l'aspect gras/brillant de la peau, de prévenir/ralentir l'hyperpigmentation post-inflammatoire de la peau et de prévenir/traiter la cellulite.
Bissett Donald Lynn
Oblong John Erich
Zhuang John Chengfeng
Gowling Lafleur Henderson Llp
The Procter & Gamble Company
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