Methods for regulating the immune response using...

Details Methods for regulating the immune response using... Methods for regulating the immune response using...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 38/17 (2006.01) A61K 38/20 (2006.01) A61K 39/44 (2006.01) A61P 37/06 (2006.01) C07K 14/705 (2006.01) C07K 16/24 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2113744

The Invention identifies the CTLA4 receptor as a ligand for the B7 antigen. The complete amino acid sequence encoding human CTLA4 receptor gene is provided. The invention provides a composition comprising a B7-binding molecule and an IL4-binding molecule for use In regulating an immune response by blocking a B7 interaction with lymphocytes.

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