Methods for rna desilylation

C - Chemistry – Metallurgy – 07 – H

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C07H 21/02 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2673538

The invention provides tetraalkyl ammonium fluoride derivatives or a pyridine hydrogen fluoride complex to remove silyl protecting groups in oligoribonucleotides synthesis.

La présente invention concerne des dérivés de fluorure d'ammonium tétra-alkyle ou un complexe de fluorure d'hydrogène pyridine pour supprimer les groupes silyle protecteurs dans la synthèse des oligoribonucléotides.

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