C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/08 (2006.01) A61K 31/496 (2006.01) A61P 25/00 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2749163
The disclosure provides methods and compositions useful for screening inhibitors of aggregation mediated proteotoxicity. The disclosure provides transgenic animals and cell useful for such screening. Also provided are compounds useful for inhibiting aggregation mediated proteotoxicity in a subject.
L'invention concerne des méthodes et des compositions utiles dans le criblage d'inhibiteurs de la protéotoxicité induite par l'agrégation. L'invention concerne également des cellules et des animaux transgéniques utiles dans ce criblage. L'invention concerne encore des composés utiles dans l'inhibition de la protéotoxicité induite par l'agrégation chez un patient.
Baiga Thomas J.
Dillin Andrew
Kapernick Erik
Noel Joseph P.
Mbm Intellectual Property Law Llp
The Salk Institute For Biological Studies
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