C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/40 (2006.01) C12Q 1/37 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2750520
The present invention relates to antibodies that bind to prorenin. In particular, the invention relates to monoclonal antibodies that bind to prorenin and inhibit the activation of prorenin. The antibodies of the invention are useful for screening for candidate agents that inhibit the activation of prorenin and candidate agents the modulate the activity of renin. The antibodies are also useful as diagnostics and for treating disease states.
La présente invention concerne des anticorps qui se lient à la prorénine. En particulier, l'invention concerne des anticorps monoclonaux qui se lient à la prorénine et inhibent l'activation de la prorénine. Les anticorps de l'invention sont utiles pour cribler des agents candidats qui inhibent l'activation de la prorénine et des agents candidats qui modulent l'activité de la rénine. Les anticorps sont également utiles comme outils diagnostiques et pour traiter des états pathologiques.
Gowling Lafleur Henderson Llp
Molecular Innovations
LandOfFree
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