C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/02 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 14/72 (2006.01) C12Q 1/04 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) G01N 33/88 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2435510
The present invention provides mehtods for screening for substances which inhibit the interaction between a FP prostanoid receptor and a compoudn having PGF2.alpha.alphaactivity, methods for inhibiting the interaction, methods of inhibiting signaling mediated by .beta.beta-catenin, and methods of treating cancer.
La présente invention concerne des procédés de criblage pour des substances qui inhibent l'interaction entre un récepteur de prostanoïde FP et un composé présentant une activité PGF¿2.alpha.?, des procédés d'inhibition de cette interaction, des procédés d'inhibition de la signalisation à médiation de .beta.-caténine, ainsi que des méthodes de traitement du cancer.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The Arizona Board Of Regents On Behalf Of The University Of Ariz
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