Methods for screening substances in a microwell array

Details Methods for screening substances in a microwell array Methods for screening substances in a microwell array

C - Chemistry, Metallurgy

40

B

C40B 60/00 (2006.01) C40B 99/00 (2006.01) G01N 35/10 (2006.01) B01L 3/00 (2006.01)

Patent

CA 2665706

Methods for manufacturing and using an apparatus for manipulating and analyzing a large number of microscopic samples of a liquid or materials, including cells, in liquid suspension. Parallel through-holes are formed in a platen and loaded with a liquid. Loading may be performed in such a way as to create a gradient, with respect to the position of the through-holes, of the concentration of a particular substance or of another quantity. Mixing of the contents of through--holes may be obtained by bringing filled microwell arrays into contact with each other with registration of individuals through-holes.

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