Methods for selective immunomodulation using pimecrolimus

Details Methods for selective immunomodulation using pimecrolimus Methods for selective immunomodulation using pimecrolimus

A - Human Necessities

61

K

A61K 31/436 (2006.01) A61K 31/353 (2006.01) A61K 31/439 (2006.01) A61K 31/4745 (2006.01) A61K 31/56 (2006.01) A61K 45/06 (2006.01) A61P 1/00 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2442969

This invention relates to methods to produce selective immunomodulation in epithelial tissues to treat epithelial inflammatory disorders. This invention provides methods for the use of pimecrolimus to treat epithelial inflammatory disorders, including asthma and inflammatory bowel disease while minimizing systemic side effects.

La présente invention concerne des procédés permettant de réaliser une immunomodulation sélective de tissus épithéliaux de façon à traiter des troubles inflammatoires épithéliaux. L'invention concerne plus particulièrement des procédés permettant d'utiliser le pimécrolimus pour traiter des troubles inflammatoires épithéliaux, y compris l'asthme et les affections inflammatoires intestinales tout en minimisant les effets secondaires systémiques.

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