A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/70 (2006.01) A61K 31/00 (2006.01) A61K 33/24 (2006.01) A61K 33/40 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) A61K 38/49 (2006.01) A61K 41/00 (2006.01) A61N 5/00 (2006.01) C07K 14/47 (2006.01)
Patent
CA 2227370
Methods of killing or inhibiting the growth of cells are disclosed. The invention provides the administration of a WAF1 inhibitor to cells which have induced a WAF1-dependent pathway. The amount of a WAF1 inhibitor which is administered to the cells is sufficient to inhibit the growth thereof or even kill the cells. The method can include subjecting the cells to a treatment which induces a WAF1-dependent pathway.
La présente invention se rapporte à des procédés pour tuer sélectivement des cellules ou inhiber la croissance de cellules. L'invention consiste à administrer un inhibiteur de WAF1 à des cellules ayant induit un processus dépendant de WAF1. La quantité d'inhibiteur WAF1 administrée aux cellules est suffisante pour inhiber leur croissance ou même tuer les cellules. Le procédé peut consister à soumettre les cellules à un traitement qui induira un processus dépendant de WAF1.
Poluha Dorota K.
Poluha Wojciech
Ross Alonzo H.
Smart & Biggar
University Of Massachusetts
Worcester Foundation For Biomedical Research Inc.
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