A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/00 (2006.01) A61K 31/167 (2006.01) A61K 31/18 (2006.01) A61K 31/4035 (2006.01) A61K 31/4418 (2006.01) A61K 31/711 (2006.01) A61K 45/06 (2006.01) C07K 14/47 (2006.01) C12N 9/16 (2006.01) C12N 15/11 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2434601
This invention relates to the inhibition of histone deacetylase (HDAC) expression and enzymatic activity. The invention provides methods and reagents for inhibiting HDAC-4 and HDAC-1 by inhibiting expression at the nucleic acid level or inhibiting enzymatic activity at the protein level.
L'invention concerne l'inhibition de l'expression et de l'activité enzymatique de l'histone déacétylase (HDAC). L'invention concerne des procédés et des réactifs permettant l'inhibition de l'HDAC-4 et de l'HDAC-1 par inhibition de l'expression au niveau de l'acide nucléique ou par inhibition de l'activité enzymatique au niveau protéinique.
Besterman Jeffrey M.
Bonfils Claire
Delorme Daniel
Fournel Marielle
Lavoie Rico
Methylgene Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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