Methods for suppressing neovascularization using ephrinb2

Details Methods for suppressing neovascularization using ephrinb2 Methods for suppressing neovascularization using ephrinb2

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61P 5/32 (2006.01) A61P 19/02 (2006.01) A61P 27/00 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2561841

Methods for inhibiting DNA synthesis, MAP kinase activation, and tube formation of endothelial cells are provided. Also provided are methods for inhibiting angiogenesis and neovascularization, as well as compositions useful for the methods described herein.

L'invention concerne des procédés permettant d'inhiber la synthèse d'ADN, l'activation de MAP-kinases, et la formation d'un tube de cellules endothéliales. L'invention concerne également des procédés permettant d'inhiber l'angiogenèse et la néovascularisation, ainsi que des compositions utiles dans la mise en oeuvre desdits procédés.

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