Methods for synthesis and uses of inhibitors of ghrelin...

Details Methods for synthesis and uses of inhibitors of ghrelin... Methods for synthesis and uses of inhibitors of ghrelin...

C - Chemistry, Metallurgy

07

K

C07K 7/00 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2739418

The invention provides inhibitors of ghrelin O-acyltransferase, and methods of making and using them. In some embodiments, the invention provides bisubstrate analog inhibitors of ghrelin O- acyltransferase, which can be effective in treating, for example, obesity and diabetes mellitus.

L'invention concerne des inhibiteurs de la ghréline O-acyltransférase et des procédés de fabrication et d'utilisation de ceux-ci. Dans certaines formes de réalisation, l'invention concerne des inhibiteurs d'analogues bisubstrat de la ghréline O-acyltransférase pouvant servir à traiter, par exemple, l'obésité et le diabète sucré.

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