C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/06 (2006.01) A61K 31/7052 (2006.01) C07H 11/04 (2006.01) C07H 15/00 (2006.01) C07H 19/10 (2006.01) C07H 19/16 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2421040
The present invention provides methods for the chemical synthesis of nucleosides and derivatives thereof, including 2'-amino, 2'-N-phthaloyl, 2'-O- methyl, 2'-O-silyl, 2'-OH nucleosides, C-nucleosides, nucleoside phosphoramidites, C-nucleoside phosphoramidites, and non-nucleoside derivatives.
L'invention porte sur un procédé chimique de synthèse de nucléosides et de leurs dérivés nucléosides, dont des nucléosides 2'-amino, 2'-N-phthaloyl, 2'-O-méthyl, 2'-O-silyl, 2'-OH, des C-nucléosides, de nucléosides phosphoramidites, de C-nucléosides phosphoramidites, ainsi que sur leurs dérivés non nucléosides.
Beigelman Leonid
Haeberli Peter
Karpeisky Alexander
Serebryany Vladimir
Sweedler David
Ribozyme Pharmaceuticals Incorporated
Sirna Therapeutics Inc.
Smart & Biggar
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