Methods for synthesizing quinolinone compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01)

Patent

CA 2543820

A method of synthesizing a substituted or unsubstituted 4-amino-3- benzimidazolyl quinolinone compound includes reacting a first compound having the formula I with a second compound having the formula II in a suitable solvent in the presence of a sodium or potassium salt of a base. The first compound and the second compound have the following structures where the variables have the values described herein.

L'invention concerne une méthode de synthèse d'un composé de 4-amino-3-benzimidazolyl-quinolinone substitué ou insubstitué, qui consiste à mettre en réaction un premier composé de formule (I) avec un second composé de formule (II) dans un solvant approprié, en présence d'un sel de sodium ou de potassium. Le premier composé et le second composé présentent les structures (I) et (II) dans lesquelles les variables ont les valeurs indiquées dans le mémorandum descriptif.

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