Methods for systematic identification of protein - protein...

G - Physics – 01 – N

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G01N 33/68 (2006.01)

Patent

CA 2430954

The present invention relates in part to a method for identifying protein- protein interactions. The interacting proteins may be isolated by affinity chromatography and may be identified and characterized by mass spectrometry. The invention in part allows for the high throughput analysis of protein- protein interactions that lends itself to automation.

L'invention concerne en partie un procédé d'identification d'interactions protéine-protéine. Les protéines qui interagissent entre elles peuvent être isolées par chromatographie d'affinité, puis identifiées et caractérisées en spectrométrie de masse. Cette partie de l'invention permet une analyse à grand débit des interactions protéine-protéine qui se prête d'elle même à l'automatisation.

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