C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 38/00 (2006.01) A61K 49/00 (2006.01) C07H 21/04 (2006.01) C12M 1/34 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2582022
The present invention relates to methods for the identification of genetic polymorphisms that may be associated with a risk for QT prolongation after treatment with iloperidone and related methods of administering iloperidone to patients with such polymorphisms.
La présente invention concerne des méthodes d'identification de polymorphismes génétiques pouvant être associés à un risque de prolongation de QT suite à un traitement à l'ilopéridone, ainsi que des méthodes associées d'administration d'ilopéridone à des patients présentant lesdits polymorphismes.
Polymeropoulos Mihael H.
Wolfgang Curt D.
Shapiro Cohen
Vanda Pharmaceuticals Inc.
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