C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2529633
The invention relates to methods for the diagnosis or prognosis of Alzheimer's disease in an individual. An inventive method has at least one step for detecting the presence or the absence of the minority allele of polymorphism rs908832 of gene ABCA2. The presence of the minority allele of polymorphism rs908832 of gene ABCA2 indicates that the individual can be afflicted with Alzheimer's disease or is presently at increased risk of developing Alzheimer's disease.
Méthodes de diagnostic ou de pronostic de la maladie d'Alzheimer chez un sujet. Ladite méthode comprend au moins une étape de détection de la présence ou de l'absence de l'allèle minoritaire du polymorphisme rs908832 du gène ABCA2. La présence de l'allèle minoritaire du polymorphisme rs908832 du gène ABCA2 indique que le sujet peut être atteint de la maladie d'Alzheimer ou bien présente un risque accru de développer la maladie d'Alzheimer.
Benavides Jesus
Cousin Emmanuelle
Deleuze Jean-Francois
Mace Sandrine
Pradier Laurent
Aventis Pharma S.a.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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