Methods for the diagnosis of glaucoma

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2204375

glucocorticoid-induced protein, TIGR, that is produced by cells of the trabecular meshwork can be used to diagnose glaucoma. The TIGR protein, anti-TIGR antibodies, and TIGR encoding sequences also provide a diagnostic for glaucoma and its related diseases.

La présente invention concerne une protéine induite par un glucocorticoïde, la TIGR, produite par les cellules du maillage trabéculaire, qui peut servir à diagnostiquer un glaucome. Ladite protéine TIGR, les anticorps anti-TIGR, ainsi que les séquences d'ADN codant pour la protéine TIGR offrent également un moyen de diagnostic du glaucome et des maladies associées à celui-ci.

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