Methods for the diagnosis, risk assessment, and monitoring...

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Details

G01N 33/48 (2006.01) G01N 33/483 (2006.01) G01N 33/49 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2693177

Methods for the diagnosis, risk assessment, and monitoring of Autism Spectrum Disorder (ASD) are disclosed. More specifically the present invention relates to the measurement of small molecules (metabolites) in human plasma that are found to have different abundances between persons with a clinical manifestation of ASD and subjects not expressing symptoms of ASD. Further, this invention relates to the monitoring of putative therapeutic strategies designed to ameliorate the biochemical abnormalities associated with ASD.

L'invention concerne des procédés pour le diagnostic, l'évaluation de risque et la surveillance de Troubles du Spectre Autistique (ASD). De façon plus spécifique, la présente invention porte sur la mesure de petites molécules (métabolites) dans le plasma humain qui sont trouvées en quantités différentes chez des personnes avec une manifestation clinique d'ASD et des sujets n'exprimant pas de symptôme d'ASD. De plus, cette invention porte sur la surveillance de stratégies thérapeutiques putatives destinées à améliorer les anomalies biochimiques associées à l'ASD.

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