A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/145 (2006.01) C07K 1/04 (2006.01)
Patent
CA 2686817
The instant invention comprises a process for selecting and manufacturing antibodies useful for therapeutic, prophylactic, diagnostic or research purposes using epitope peptide mixtures synthesized by the solid phase synthesis, such process defined by a set of rules regarding the identity and the frequency of occurrence of amino acids that substitute a base or native amino acid of a known epitope. The resulting antibodies are related to but distinct from antibodies that bind to the known epitope.
La présente invention concerne un procédé de sélection et de fabrication d'anticorps utiles dans les domaines de la thérapie, de la prophylaxie, du diagnostic ou de la recherche. Lesdits anticorps utilisent des mélanges de peptide d'épitope synthétisés par la synthèse en phase solide. Un tel processus est défini par une série de règles relatives à l'identité et à la fréquence de l'occurrence des acides aminés qui substituent une base ou un acide aminé natif d'un épitope connu. Les anticorps résultant sont liés aux anticorps qui se lient à l'épitope connu, mais distincts desdits anticorps.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Peptimmune Inc.
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