Methods for the early diagnosis of ovarian cancer

Details Methods for the early diagnosis of ovarian cancer Methods for the early diagnosis of ovarian cancer

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 38/48 (2006.01) C07H 21/04 (2006.01) C07K 1/00 (2006.01) C12Q 1/37 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2519193

The present invention discloses the protease stratum corneum chymotrytic enzyme (SCCE) is specifically over-expressed in ovarian and other malignancies. A number of SCCE peptides can induce immune responses to SCCE, thereby demonstrating the potential of these peptides in monitoring and the development of immunotherapies for ovarian and other malignancies.

Selon la présente invention, l'enzyme chymotrytique de couche cornée (SCCE) est sur-exprimée de façon spécifique dans le cancer malin de l'ovaire entre autres cancers malins. Certains peptides de SCCE peuvent induire une réponse immunitaire à la SCCE, démontrant ainsi l'utilité potentielle de ces peptides dans le contrôle et le développement de thérapies immunitaires du cancer malin de l'ovaire entre autres cancers malins.

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