C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C40B 30/04 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2660275
The present invention is directed to the identification of predictive markers that can be used to determine whether patients with cancer are expected to demonstrate long term or short term survival times. In particular, the present invention is directed to the use of certain individual and/or combinations of predictive markers, wherein the expression of the predictive markers correlates with expected short term or long term survival. Thus, by examining the expression levels of individual predictive markers and/or predictive markers comprising a marker set, it is possible to determine predicted patient survival.
La présente invention concerne l'identification de marqueurs prévisionnels qui peuvent être utilisés pour déterminer si des patients cancéreux sont supposés manifester des temps de survie à long terme ou à court terme. La présente invention concerne en particulier l'utilisation de certains marqueurs prévisionnels individuels et/ou combinés, l'expression des marqueurs prévisionnels correspondant à la survie à court terme ou à long terme escomptée. En conséquence, en examinant les niveaux d'expression de marqueurs prévisionnels individuels et/ou de marqueurs prévisionnels contenant un ensemble de marqueurs, il est possible de déterminer la survie prédite d'un patient.
Bryant Barbara M.
Damokosh Andrew I.
Mulligan George
Millennium Pharmaceuticals Inc.
Robic
LandOfFree
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