Methods for the identification of microrna and their...

C - Chemistry – Metallurgy – 40 – B

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Details

C40B 40/06 (2006.01) C07H 21/02 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) C40B 30/00 (2006.01) C40B 30/02 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2628941

The present invention concerns a method for prediction and identification of microRNA precursors (pre-microRNA) and microRNA molecules using data processing programs and databases. The invention also pertains to the isolated form of these pre- microRNAs, microRNA molecules and derived nucleic acids there of. The invention also relates to recombinant vector, host cell, support, pharmaceutical composition or kit comprising such microRNA molecules or there of derivated molecules. The invention also applies to the use of such microRNA molecules and/or their identified targets in research, prognostic, diagnostic tools/methods as well as for therapeutic applications.

La présente invention concerne un procédé permettant de prédire et d~identifier des précurseurs du microARN (pré-microARN) et des molécules de microARN à l~aide de programmes de traitement des données et de bases de données. L~invention concerne également la forme isolée de ces pré- microARN, des molécules de microARN et des acides nucléiques dérivés de ceux-ci. L'invention concerne également un vecteur recombinant, une cellule hôte, un support, une composition pharmaceutique ou un kit comprenant de telles molécules de microARN ou des molécules qui en sont dérivées. L~invention concerne également l~utilisation de telles molécules de microARN et/ou de leurs cibles identifiées dans des outils / procédés de recherche, de pronostique et de diagnostique ainsi que dans des applications thérapeutiques.

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