C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/06 (2006.01) C07D 493/04 (2006.01) C12P 17/16 (2006.01) C12P 17/18 (2006.01)
Patent
CA 2499600
The present invention relates to improved methods for the production, isolation and purification of epothilone B. These methods include, for example, a fermentation process for the production of epothilone B, isolation via adsorption onto a resin, and subsequent purification.
L'invention concerne des procédés améliorés de production, d'isolation et de purification d'épothilone B. Ces procédés comprennent, par exemple, un processus de fermentation pour la production d'épothilone B, d'isolation via l'adsorption sur une résine et de purification subséquente.
Benigni Daniel
Chiang Shu-Jen
Comezoglu Fahri T.
Davis Brian L.
Eagan Bruce
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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