Methods for the prevention and treatment of cancer using...

Details Methods for the prevention and treatment of cancer using... Methods for the prevention and treatment of cancer using...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 39/44 (2006.01) A61P 35/00 (2006.01) C07K 16/44 (2006.01)

Patent

CA 2429987

The present invetion relates to mehtods of treating and preventing cancer in an animal comprising administrating to said animal antibodies specific for C3b(i). The present invention also realtes to mehtods of treating and preventing cancer in an animal comprising administering to said animal IgG antbodies, IgM antibodies and/or complement components in combination with antibodies immunospecifically bind to one or more cancer cell antigens in combination with antibodies immunospecific for C3b(i). The present invention further relates to pharmaceutical compositions for the treatment and prevention of cancer comprising one or more antibodies immunospecific for C3b(i) and one or more antibodies immunospecific for one or more cancer cell antigens.

La présente invention porte sur des procédés de traitement et de prévention du cancer chez un animal. Ce procédé consiste à administrer à cet animal des anticorps spécifiques de C3b(i). L'invention porte également sur des procédés de traitement et de prévention du cancer chez un animal qui consistent à administrer à celui-ci des anticorps IgG, des anticorps IgM et/ou des composants de compléments en combinaison avec des anticorps immunospécifiques de C3b(i). L'invention porte aussi sur des procédés de traitement et de prévention du cancer chez un animal qui consistent à administrer à ce dernier des anticorps qui se lient de manière immunospécifique à un ou plusieurs antigènes de cellules cancéreuses en combinaison avec des anticorps immunospécifiques de C3b(i). Cette invention porte également sur des compositions pharmaceutiques utiles dans le traitement et la prévention du cancer et comprenant un ou plusieurs anticorps immunospécifiques de C3b(i) et un ou plusieurs anticorps immunospécifiques d'un ou plusieurs antigènes de cellules cancéreuses.

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