A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/00 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/4162 (2006.01) A61K 31/44 (2006.01) A61K 31/46 (2006.01) A61P 1/00 (2006.01) A61P 5/00 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2647903
The present invention relates to functional proteins encoded by nucleic acid sequences comprising a nonsense mutation. The present invention also relates to methods for the production of functional proteins encoded by nucleic acid sequences comprising a nonsense mutation and the use of such proteins for prevention, management and/or treatment of diseases associated with a nonsense mutation(s) in a gene.
L'invention concerne des protéines fonctionnelles codées par des séquences d'acide nucléique comprenant une mutation non-sens. L'invention concerne également des méthodes de production de protéines fonctionnelles codées par des séquences d'acide nucléique comprenant une mutation non-sens et l'utilisation de ces protéines pour la prévention, la gestion et/ou le traitement de maladies associées à une ou plusieurs mutations non-sens dans un gène.
Almstead Neil G.
Chen Guangming
Hirawat Samit
Hwang Seongwoo
Karp Gary M.
Osler Hoskin & Harcourt Llp
Ptc Therapeutics Inc.
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