Methods for the purification of levofloxacin

Details Methods for the purification of levofloxacin Methods for the purification of levofloxacin

C - Chemistry, Metallurgy

07

D

C07D 413/04 (2006.01) C07D 498/06 (2006.01)

Patent

CA 2466860

Levofloxacin has been purified by dissolving levofloxacin in a polar solvent at an elevated temperature and crystallizing purified levofloxacin. Preferably, an antioxidant is added to increase the purity.

Selon l'invention, la levofloxacine est purifiée par dissolution de celle-ci dans un solvant polaire à une température élevée et par cristallisation de la levofloxacine purifiée. De préférence, un antioxydant est ajouté aux fins d'augmenter sa pureté.

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