Methods for the treatment of anxiety and for identification...

Details Methods for the treatment of anxiety and for identification... Methods for the treatment of anxiety and for identification...

A - Human Necessities

61

K

A61K 38/08 (2006.01) A61K 48/00 (2006.01) A61P 25/22 (2006.01)

Patent

CA 2619481

Methods for the treatment of neuropsychiatric disorders such as anxiety are disclosed. The methods involve modulating the expression of the angiotensin IV receptor or modulating the biological activity of the angiotensin IV receptor by utilizing antagonists to the receptor. Also disclosed are methods for identifying antagonists of the angiotensin IV receptor that are effective to reduce anxiety in a subject.

Cette invention porte sur des méthodes de traitement de troubles neuropsychiatriques tels que l'anxiété. Ces méthodes consistent à moduler l'expression du récepteur de l'angiotensine IV ou à moduler l'activité biologique du récepteur de l'angiotensine IV au moyen d'antagonistes de ce récepteur. Cette invention concerne également des méthodes d'identification d'antagonistes du récepteur de l'angiotensine IV qui peuvent efficacement réduire l'anxiété chez un sujet.

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